[dumb1224]

> For example, what’s the end game for the cellular signaling modeling outlined in the article?

I think the article meant to refer to systems biology (as in a new field). It's not exactly a single 'model' rather a methodology as far as I know. Also the 'end game' IMO in bioinformatics the goal is mostly to discover new knowledge rather than having a 'production ready' model. Through the 'big data' science one could uncover hidden biological effects, new mechanism and new insights etc. Each of these big data modelling exercise is really to push the biology forward to a deeper level. In a way it can be comparable to astrophysics (is it a coincidence that many people working in bioinformatics have an astrophysics background)?