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by alicemaz
2135 days ago
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oh interesting. I've had a pet theory for awhile now re: trans/autism comorbidity that they're better thought of as symptoms (among others! op's link notes higher incidence of every surveyed mental disorder) of some underlying brain abnormality, rather than being tangled up in some causal relationship with each other. had not heard of gender incoherence theory before |
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Many of the genes that control brain development are also linked to sex differentiation, and so it not surprising to me that in the presence of greater number of mutations (technical term) in these genes, the more sexual development will be differentially regulated, and will follow a different trajectory. I suspect, but do not know how to model, that this would tend to result in less sexual differentiation, making the binary male/female extreme phenotypes less likely in ASD.