[tehjoker]

Any given layout is pretty easy to work. The problem is the sheer number of form factors, flexible resizing, and rendering methods (as you mentioned, print vs AMOLED vs monitors) that make designers and engineers cry.

When I talk to designers, they love love love paper for many reasons, but one of them is the total control they have over the medium and the fact that they only have to deal with one fixed form factor at a time.