[maxbond]

I'm sure that's tremendously helpful but isn't exactly an antidote, is it? You can't really simulate an unforeseen situation. If you can simulate it accurately - then you've foreseen it, and are thus able to account for all relevant variables. If you are randomly generating scenarios, something like fuzz testing or property testing, then I am sure you will discover bugs before they hit production, but you can't be sure you're simulating it accurately.

For example, maybe when your car is T-boned while climbing a steep hill, the suspension behaves in a way you didn't expect and which isn't replicated by your simulation. Or maybe you're sent a batch of decals with bad adhesive, and in the hot sun the begin to slip down the windshield until they end up obscuring or otherwise interfering with a sensor.

The only simulation that can account for every variable, regardless of whether you've anticipated it, is reality.