A single virus probably can cause infection, but it appears not to be anywhere near a linear correlation between dose and risk. And severity can be tied to initial dose, too.
This is one interesting thing about masks: they may do more to improve prognosis than reduce infection.
Further, when we're talking about ... e.g virus on cardboard... the way you do the test is after the droplet on the cardboard has dried, you use a buffer to dissolve the virus back out of the cardboard and see if you can grow it in culture. This may recover virus in cases where there's absolutely no chance for casual contact to get it out.
there is such a thing as minimal infective dose. they do not know what the minimal infective dose is yet though. there is no you get one virus particle and now you have the virus... rather, you have a worked out average dose of the virus particles that if you gave a population of people that much of the virus 50% of them would become ill.
A single virus probably can cause infection, but it appears not to be anywhere near a linear correlation between dose and risk. And severity can be tied to initial dose, too.
This is one interesting thing about masks: they may do more to improve prognosis than reduce infection.
Further, when we're talking about ... e.g virus on cardboard... the way you do the test is after the droplet on the cardboard has dried, you use a buffer to dissolve the virus back out of the cardboard and see if you can grow it in culture. This may recover virus in cases where there's absolutely no chance for casual contact to get it out.