[solinent]

There are also structural changes in the brain as time passes, and hopefully biological ones as well if I'm going to digest this food I just ate. What structural changes are present and can these changes be used to diagnose the condition? Are these changes necessary for the condition? To me it looks like gray matter loss is not exclusive to this condition, these studies only quantify brain matter density, not structure. This study is also not very well designed, it only studies BPD patients without studying patients that may potentially have the identified defect but not the diagnosis.

Our diagnosis of psychological conditions is very vague as well--is bipolar disorder diagnosed as lack of gray matter? If it's not, then why not?

[blame_lewis]

I'm pretty sure there is more extensive literature involving the exact types of degradation that is characteristic to the disease, but I do not think I'm competent to cite it correctly.

I'd imagine this process isn't so great for diagnosis given that it's mostly been observed in people with decades of uncontrolled disease behind them.