[catwind7]

nand2tetris is a great course that shows you how to design a computer from the chip level, build an assembler, and write a high level language + compiler that eventually produces the assembly code for the machine architecture _you_ built. I highly recommend it.

[kerkeslager]

nand2tetris is awesome, and taught me a large portion of the little I know on this subject.

The real barriers to me at this point are targeting a pragmatic real-world architecture.