[laurademing]

Hi guys! This is Laura :) - everyone here is really cool and I can't believe this made the front page of HN so just wanted to drop my email here in case anyone wants to catch up on longevity stuff or other cool science discussion - [e-mail]. Sorry, I just really love geeking out and this seemed like a good place to find more thought buddies. Anyway, I love talking about most interesting things (physics / how computers work / all the stuff I don't know) so if you're down for it drop me a line!

(not sure how to verify but that's the email associated w all my public stuff / twitter posts so hopefully that's enough)

[d136o]

There seems to be research exploring links between blood sugar regulation (diabetes) and aging. I guess that shows up in metformin <-> aging correlations/links.

Do you have pointers to research linking liver function to diabetes and perhaps to aging research.

It’s known that non alcoholic fatty liver is common in people who will develop type 2 diabetes. But the link is not well understood. (There doesn’t seem to be a consensus on how the two are linked?).

Any solid references would be helpful, I’ve only found older nature reviews from 2006 and 2010. Maybe that’s the state of understanding but curious to get any additional pointers.

Asking for a friend :)

[zanybear]

Peter Attia talks about metformin (https://peterattiamd.com/) also in the context of exercise and I've heard Dave Asprey (https://daveasprey.com/)talking about it.

[1996]

Thanks! Do you have a list of which simple interventions have the most data behind (ex: metformin, resveratrol?), and which long shots have the most potentials (ex: rejuvenating stem cells by expressing Yamanaka factors, then reinjecting them, as bone marrow transplants have shown the new cells find their way in about every tissue)