[eebynight]

You must not know too many people that have taken statins...

Sure, on paper, the LDL number goes down and according to the numbers you have a lower risk of heart attack, but the one common thing I've notice is that everyone complains that they feel terrible. Things like dizziness, nausea, low energy/libido, etc...

Let's not forget that it takes mainstream science time to catch up to new research. There is a lag in existing beliefs while more research is being done and evidence solidified.

That being said, lipidology is extremely complex but in the case of low carbohydrate diets the issue of having high LDL and HDL may not be as bad as mainstream medicine would make it out to be.

For some interesting insights on research being conducted in this field, Thomas Dayspring and Dave Feldman are extremely knowledgable and explain things quite well.

https://twitter.com/Drlipid

https://cholesterolcode.com/

They both have appeared on a number of health/fitness related podcasts but a quality one they both have been on is "The Drive" by Peter Attia:

https://peterattiamd.com/tomdayspring1/

https://peterattiamd.com/davefeldman/

edit: I would also argue that his subjective feelings of good health are a much better indicator than the population-averaged cholesterol numbers...

edit2: to say that this type of research is outside of mainstream medical advice is misleading. Lipodology is a prominent topic and a quick pubmed search for the "lipid" keyword since 2018 shows over 60k results. In medicine there is rarely a such thing as "settled" science. Things are continuously researched with new questions and information is used to update our original hypothesis. To refer to current advice as set in stone is very naive...

[JamesBarney]

> That being said, lipidology is extremely complex but in the case of low carbohydrate diets the issue of having high LDL and HDL may not be as bad as mainstream medicine would make it out to be.

I'd 100% agree with this. But "your cholesterol sky rocketing a good sign" is not something the evidence currently shows.

> that everyone complains that they feel terrible. Things like dizziness, nausea, low energy/libido, etc...

Statins definitely have side effects, just on balance it leads to better cognitive outcomes instead of worse ones.

It's true that it takes time for mainstream science to catch up. But new preliminary research is new and preliminary and when it goes wrong it goes wrong more catastrophically than solid mainstream science.

[eebynight]

> I'd 100% agree with this. But "your cholesterol sky rocketing a good sign" is not something the evidence currently shows.

"sky-rocketing" is a definite over-exaggeration here.

I would be curious to see what your response is to the link I posted in another comment here.

I am wondering how people that still reference these dated outlooks on cholesterol can explain why there is insufficient evidence of higher cardiovascular disease rates in those with high LDL in the presence of high HDL and low triglycerides, commonly called the "lipid triad"?

https://cholesterolcode.com/a-dialog-on-the-lipid-triad-with...

What the parent comment initially stated would lead me to believe that he falls into this lipid triad group and if I was in his shoes I would tell any doctor that recommended a statin to f* off if I had just started feeling the best I'd ever had in my life.

Also, can you send me some research for your points about statins having an increase in cognitive function? My understanding was that many were arguing the opposite and some meta-reviews I read on the topic suggested that more evidence was needed to make any clear observations.