[NateEag]

I believe that macros can increase the complexity of debugging.

However, I believe they're much more debuggable than dynamically-generated functions in most languages. There's another layer of translation from your baseline code, but due to the nature of macros, you can usually just step right into them and see the expanded, generated macro code, if my rusty memories of debugging elisp are correct.

Here's one person reading about Common Lisp's debugging infrastructure, FWIW.