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by gtrubetskoy 2201 days ago
I wouldn't rank glucose above fats. As I understand it, it's not exactly a "shorter battery" than fat - it is simply a form of energy that is abundant in plant life, but fat is still a (much) "better battery".

The reason our body always favors burning glucose first is NOT because glucose is "better" but actually because it is an inferior type of fuel (it creates "pollution" and is difficult to burn - you can develop diabetes from too much of it) - so our evolved system tries to get rid of it first, while hanging on to the "good stuff" for as long as it can.

2 comments

> The reason our body always favors burning glucose first is NOT because glucose is "better" but actually because it is an inferior type of fuel (it creates "pollution" and is difficult to burn - you can develop diabetes from too much of it) - so our evolved system tries to get rid of it first, while hanging on to the "good stuff" for as long as it can.

This is not the standard textbook biological view of the bodies use of glucose and fats.

I'm all for having heterodox opinions but I think you should let people know what is a heterodox position, and provide more supporting evidence than when giving a textbook explanation.

You don't develop type 2 diabetes from being fat, you develop diabetes from high average blood glucose levels triggering insulin resistance.

Also, what is the pollution you are talking about? From what I understand, lipolysis generates ketones, which at normal lipolytic amounts aren't toxic.

https://en.wikipedia.org/wiki/Type_2_diabetes?wprov=sfla1

> Also, what is the pollution you are talking about?

For example reactive oxygen species.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865572/

Oh I see now that I read your parent comment completely wrong, you are right. Sorry, thanks for the citation!