[kpfleger]

Every time a new D & C19 item comes up, 75+% of the comments are already addressed in my review: http://agingbiotech.info/vitamindcovid19/ This new study is already incorporated there with a couple paragraphs of good discussion in strengths, weaknesses, importance, etc. Broadly, it's consistent with prior evidence but significant for being the 1st controlled trial (even if not random, which would be unethical at this point and thus should be impossible now). It's too bad the control group had so much more comorbidity. Hopefully their multivariate model is trustable for taking baseline differences in the 2 arms into account. The effect size is huge (OR=0.15).

Other common comment topics here (correlation vs causation, sun exposure, burden of proof for correcting deficiency, etc.) are all covered in the review already. If something important isn't covered, email me.