[gator-io]

The corruption of science should be aggressively confronted.

If you dig into Surgisphere, you will see they have significant consulting engagements with Johnson and Johnson. Not saying that's necessarily bad, but so much bad science about Covid and HCQ seems geared towards promoting high-priced treatments like Remdesivir, and not low-cost preventative measures like making sure you're not D deficient. All these studies need to be evaluated based on who's funding them or the political agenda behind them.

HCQ seems like it's been targeted for destruction. Every study I've read on it shows you shouldn't use it in late stages of disease. Fair enough, but the theory of its effectiveness (as a Zinc ionophore) hasn't been fully studied, although there is a good amount of anecdotal and country-level evidence it works well if taken early (with Zinc).

These garbage studies are dangerous and should be called out loudly.

[inasio]

This is a pretty simplistic view, the article talks about a different Surgisphere study where the conclusion is that a cheap and widely available drug is effective against covid-19 (the study also has its problems though):

"A third COVID-19 study using Surgisphere data has also drawn fire. In a preprint first posted in early April, Surgisphere founder and CEO Sapan Desai and co-authors conclude that ivermectin, an antiparasitic drug, dramatically reduced mortality in COVID-19 patients. In Latin America, where ivermectin is widely available, that study has led government officials to authorize the drug—although with precautions—creating a surge in demand in several countries."

[gator-io]

I pointed out the Johnson and Johnson relationship only to say motives should be examined.

Surgisphere is producing studies based on data they don't actually have, according to researchers, Australian hospitals, etc. It could be for self-aggrandizement, or pay-for-publish or something else. I don't know, but it should not be tolerated for any reason.

[jbritton]

I have been wondering why so many HCQ studies do not include Zinc. A couple months ago I watched a video that detailed how Zinc once inside a cell could block replication of coronaviruses. And that HCQ being a Zinc ionophore gets the Zinc into the cell. The relevant study was published approximately 10 years ago.

[javagram]

Zinc has been pushed as a cure/treatment for common cold for decades.

The actual track record of whether the OTC zinc tablets you can buy in a store work is quite uncertain though. Lots of studies coming down one way or another, and uncertain levels of statistical rigor. https://www.mayoclinic.org/diseases-conditions/common-cold/e...

It is easy enough to make a video with what seems convincing but many of these neat explanations don’t actually work once you get into the human body.

[skeletor_999]

It could be that there are multiple proposed mechanisms, and that HCQ being a zinc ionophore is only one of them. I looked up some of the studies of HCQ in different animal models, and some of them showed positive results with CQ or HCQ alone.