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by scottlocklin 2215 days ago
Your statement contradicted itself in several places: a "gain of function" virus would contain random differences, and would look indistinguishable from something "created by nature." Effectively that's how nature makes more virulent viruses; the more virulent examples reproduce more effectively. Just like that's how nature/bakeries makes yeast that works better on flour. No genetic engineering involved.

I don't think there is any evidence of this, despite the usual suspects (neocon types on our side, and militarists on the Chinese side) ginning up the case for an "escape from lab" casus belli, but let's get the facts straight.

1 comments

> a "gain of function" virus would contain random differences, and would look indistinguishable from something "created by nature."

No, a chimeric virus created in a gain-of-function experiment would look extremely similar to known viruses, because these chimeras are created by combining elements of known viruses. It would not be 4% different from the closest known natural virus. Accumulating thousands of mutations throughout the entire genome takes decades of evolution. In the wild, that means thousands of generations of hosts.

A virus created in a gain-of-function experiment would also use a well-known backbone. It would not be based on some virus that nobody had ever heard of.

Yeah dude that could never happen. Except it already did:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797993/

https://norkinvirology.wordpress.com/2015/12/04/genetically-...

https://www.pnas.org/content/113/11/3048

I don't know what your purpose is in regurgitating verifiable but admittedly realistic-sounding bullshit on hacker news, but virtually every statement you have made here is obvious bullshit.

I don't even particularly believe the "possibly released from a lab" meme, and am generally against the shadowy dipshits that push it. But you're not helping here.

What happened?

Are you saying that a chimeric virus created in a lab was found to have thousands of seemingly random mutations throughout its genome?

Or are you claiming that a chimeric virus was created using a backbone that nobody had ever heard of?

Be specific, because it's impossible to respond if you vaguely call what I'm saying BS.