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by zbjornson 2209 days ago
Well, for one, orthopoxviruses cause skin lesions, replicate in keratinocytes, dermal fibroblasts and other skin cells and evoke strong immune responses there. Coronaviruses don't.
1 comments
pmayrgundter 2209 days ago
I've been looking into this.. you might be interested in my work on a Live Virus Skin Vaccine for CoV2. Comments welcome!

https://docs.google.com/document/d/1x91Ef7G6xbm77DcRDvjAXbFm...

link