[toufka]

Would the use of the Adenovirus vector used here foreclose future gene therapies delivered with a similar vector? If so, that could devastate in one go a lot of people’s ability to get specific therapies as they start to come online in the next decade.

[lbeltrame]

It is actually a very known problem for gene therapies. IIRC, similar vectors were used in the past, with the same problem, of course.