I'd say a lot depends on how much stuff you're doing every frame. From what I've seen, Epic is emphasizing you should avoid running blueprints every tick, and instead use event-driven programming heavily (or "steal" ticks from input handling), and then flip appropriate switches to remove anything that doesn't need updating every frame from even being issued a tick by the engine.
I'd say a lot depends on how much stuff you're doing every frame. From what I've seen, Epic is emphasizing you should avoid running blueprints every tick, and instead use event-driven programming heavily (or "steal" ticks from input handling), and then flip appropriate switches to remove anything that doesn't need updating every frame from even being issued a tick by the engine.