[ncmncm]

TLB shootdowns are a product of multithreading, and of unmapping memory. Avoid one, the other, or both, and TLB shootdowns fade out of the picture.

You still have cores to isolate, busybody kernel threads to suppress, and hardware interrupts to direct elsewhere, but TLB shootdown paranoia is largely a product of the current fashion favoring multi-threading over running separate processes with carefully chosen sharing.