[ben7799]

The knobs actually don't behave linearly on a tube screamer. Even the "tone" knob (EQ) doesn't behave at all linearly like you might expect out of consumer audio gear. Tube Screamers have an S-curve potentiometer in use for that knob.

That would be part of the problem with this approach.

Also with this approach you pretty much have to train the model with a near infinite collection of guitars in front of the model and a near infinite number of other effects turned on and off in front of the model.

[Scene_Cast2]

The knobs don't have to be linear at all, just differentiable - that's the beauty of ML.

As for the collection of guitars and samples - not necessarily, it would depend on how you set up the training.