Why would you? lz4 decompresses at ~5GB/s on a modern CPU [1] with good compression ratios, that's still more than most SSDs can push nowadays. Most applications are small fraction of that size on-disk.
The problems arise when you start using xz-compressed squashfs images. LZMA2 is optimized for compression ratio and typically decompresses several times slower than even zlib deflate (which is already ~10 slower than lz4).
The problems arise when you start using xz-compressed squashfs images. LZMA2 is optimized for compression ratio and typically decompresses several times slower than even zlib deflate (which is already ~10 slower than lz4).
[1] https://github.com/lz4/lz4