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by TheAdamAndChe
2243 days ago
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Without looking into the pharmacology of modafinil, this is a baseless comment. Seriously, look at the pharmacology of modafinil[1] and compare it to methylphenidate[2]. Modafinil may have some dopamine reuptake inhibition, but its affect on histamine receptors counters a lot of the hedonistic response that comes with methylphenidate. Speaking as someone with a modafinil prescription and that has taken Vyvanse, the experience is extremely different. I don't feel an urge to take more modafinil, and I don't feel extreme fatigue when taking a break from it. I'm taking a break from it now in fact. [1] https://en.wikipedia.org/wiki/Modafinil [2] https://en.wikipedia.org/wiki/Methylphenidate |
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