[Dunan]

Seconding all of this; Human Revolution is an amazing game that will stick with you for a very long time -- even more so if you have a disability that human augmentation (one of the main themes of the game) could reverse.

I play this again every few years and am always discovering more. The sequel, Mankind Divided, is better technically but goes full-on into the dystopian scenario of the first Deus Ex, whereas HR was (at the time) something of a reboot and you could play it with the goal of preventing that future. (There are multiple endings, and one or two lead to DX1's future and at least one of the others is more optimistic and does not; the directors chose dystopia for the sequel.)

If you liked Michael McCann's soundtrack for HR, definitely check out his work for X-Com and Splinter Cell: Double Agent; more of the same excellence.