[mcintyre1994]

> As a reminder, the vaccine Pandemrix, which was developed as a treatment for the swine flu, caused narcolepsy in over 1000 patients.

Another comment expanded on this that it's 3.6 additional cases per 100,000 vaccinated. For people like me lacking context and knowledge in this area, what's the 'gold standard'? Is the expectation that a vaccine has no long lasting impacts beyond the immunity it gives, and any increase at all in anything would be considered unacceptable? Or is there some complexity in that calculation?