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by mcarmichael 2243 days ago
Derek Lowe is terrific in communicating complex ideas in the field to concerned lay observers like me; he's been a great resource for reliable information about the science of this thing.

Just to clarify; the ChAdOx1 MERS prospect hasn't proceeded to a trial demonstrating efficacy in human subjects (as yet).

That's a particularly important distinction here, given the nature of the novel delivery mechanism[1] and prior observation of complications in SARS-CoV-1 vaccine development[2]

[1] https://en.wikipedia.org/wiki/Viral_vector#Adenoviruses

[2] https://www.hkmj.org/abstracts/v22n3%20Suppl%204/25.htm

1 comments

> Just to clarify; the ChAdOx1 MERS prospect hasn't proceeded to a trial...

Looks like it has (for SARS-CoV-2 instead): https://www.genengnews.com/news/astrazeneca-joins-u-of-oxfor...