[didericis]

Out of all those problems I'd say the most difficult one to tackle is related to performance, but if it's an api that only you are hitting, you can usually avoid doing anything too costly.

The recommended solution of using graphql on the server for the server/client data mismatch problem is a good one, but it's not really applicable in your case. That's geared towards people using both javascript and nodejs. If you're using javascript on the frontend and python on the backend, you can't share code/there's inevitably going to be a mismatch. A mismatch isn't always a bad thing, either; often you don't need to expose all of the database models to the client, and want a lighter weight abstraction.