[dude_bro]

One of my managers during an internship in college was blind. I actually had no idea he was blind until I met him in person; this includes being interviewed by him remotely and have discussions about code I was writing in real time. I was completely shocked.

This was at a very large corporation, and he had been blind throughout his long career there. I believe the primary tools he used were JAWS and a device that would actually generate braille for text on screen. This was pretty incredible to me, as he would do most of his reading via this braille device.

I don't think you will be limited to a certain portion of the stack. In some ways, it may open up certain opportunities like working more on the Accessbility features for front-ends, which is a critical part of a front-end but often overlooked.