IMO only if you are using the Logs functionality. You can log exceptions/errors, and it should be pretty easy to set-up monitoring around these events.
As a Datadog customer, I still use Sentry next to it, mostly for the top notch exception grouping, reporting etc. It’s just their core product, they’re better at it when you need to zoom in and actually debug.
For the bird’s eye view, Datadog is fine.