[dpratt71]

There are no guarantees in life, but the reason we don't have global pandemics constantly is that mutations that make a virus as dangerous as SARS-Cov-2 are quite rare.

[jfoster]

There actually has been quite a lot of pandemics over the past 100 or so years. Covid-19 has yet to eclipse at least 3 of them. (1918, 1957, 1968)