[ajosh]

I really like duplicati. It works in Linux, Windows and MacOS. It has good support for tons of back ends for storage (nfs, cifs, dropbox, s3, ssh, etc). The software is FOSS and it has a design that is well suited to cloud storage: it makes blocks of changes that are encrypted. As long as you have the password, it can use just those blocks to decrypt and restore.

It does automated restore tests. Setup is pretty easy. You install it, navigate to the internal web page and follow the wizard. It has sane defaults but you can change it to skip stuff you don't want backed up.

Duplicity is OK but it tends to be pretty CPU heavy when it runs and you can't control when it runs with much granularity. I used to use and like CrashPlan but its current pricing model doesn't work well for my home environment.Granted, my backups weren't huge so the memory usage of CrashPlan was OK for me.