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by IkmoIkmo 2288 days ago
I really don't see the issue. All vitamin d sales come with daily dosage information. There's (always going to be) some issues with literacy to understand this information, but that's it.

If you follow the daily dosage information, you won't even get near harmful levels of vitamin d. Recommended is about 600 IU daily. If you take 60.000 on a daily basis for months, you build up toxicity.

For that you typically need to take 30 pretty strong 2000 UI pills on a daily basis for months, while ignoring the label that states each pill is typically 250% of the daily recommended amount, and the instruction which notes the tolerable levels max out at just two daily pills.

Toxicity is extremely uncommon. Whereas deficiency is extremely common. Up to a billion people are expected to have some form of vitamin d deficiency.

That's not to say it's not a problem, but rather that it's very rare, nothing like say an opioid overdose problem. As with all things, balance is key. You can overdose on 5 cents of water in the span of 5 minutes. Acute vitamin d overdose is known to happen if you take something like 300-1000 pills of 2000 UI over a period of days, which is pretty insane.

2 comments

You reminded me of a paper that suggested that there was an error made in developing the RDA of Vitamin D; the 600IU RDA may be wildly wrong.

“ It also estimated that 8895 IU of vitamin D per day may be needed to accomplish that 97.5% of individuals achieve serum 25(OH)D values of 50 nmol/L or more.”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210929/

It's important when megadosing vitamin D to be getting enough magnesium, and to make sure you're taking it earlier in the day, so as not to disrupt your circadian rhythm.