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by hackeerTwo 2295 days ago
> The other major disadvantage is that these drugs can interact with protease inhibitors

What are the possible consequences of this?

1 comments

Death.

Kaletra, a protease inhibitor, is a combination of two drugs, one of which is a CYP3A4 inhibitor. It is used with some success on coronavirus patients.

Co-administering this with chloroquine 500mg/BID could easily result in chloroquine concentrations well above LD50.