[imjasonmiller]

The much weaker gravity and its effects on human health is something I rarely see mentioned.

If one were to be born on a body with a much weaker gravity than Earth, e.g. Mars (0.38) or the Moon (0.17), wouldn’t this confine them to bodies where gravity is less than or approximately equal?

[ufmace]

The best answer right now is that nobody has any idea what, if any, effect that would have on human health. It hasn't been tried yet, so we just don't know.