[Prrometheus]

I've heard of people having issues with DMT and LSD, of the four you mentioned, though they might have been dosage issues.

Weed is the only one of the four you mentioned that I would have no trouble with doing if it were presented to me, and DMT is the only one that I would definitely not do without more research.

[SCVirus]

And yet you do DMT everytime you sleep (most likely), and certainly it is released during near death experiences. Unlike all of the other substances mentioned it is is produced by the human brain, and is the cause of many natural brain states.

(I do not, of course, recommend anyone go out and try DMT without first experiencing other psychedelics in the order given, or in fact without doing the research.)

I highly recommend you do that research.

http://erowid.org/

http://wikipedia.org/

Psychedelic use is not to be taken lightly. It is not a form of recreation (shouldn't be), it is a method of deep introspection, of breaking down mental barriers, a journey within yourself (among other things which really cannot be explained until you have reached the state of understanding that usually occurs with mush or mescaline use. This too is not an absolute, but is common to most peoples 'route' in this journey.)

Use of entheogens is, of course, not the only route to these states, tantric yoga can perform the same function as cannabis, and years (or decades) of deep meditation can take replace the use of mush, LSD and DMT.