[nonbirithm]

Google hosts YouTube and the ads for YouTube on the same domain with obfuscated paths, so that won't work. About all you can do if you want to use the app is pay for premium or use something like Vanced which unlocks the premium features without paying.

The main reason content blocking works is because anyone can introspect webpages and the source is available for modification. When things become byte-compiled it gets exponentially harder, if not impossible.