[bitxbit]

Imagine Excel with Python.

Edit: I believe Libre has python.

[warpech]

https://www.xlwings.org/

[thanatropism]

I made some code using xlwings to allow you to emulate spreadsheets with machine learning models à la scikit-learn.

https://github.com/asemic-horizon/stanton

[estebank]

That's what Resolver One used to be. Sadly, it didn't survive.

https://youtu.be/u6EV2jiKRfc