[samdunham]

That may not actually be true:

https://www.tampabay.com/news/health/study-finds-nicotine-sa...

[AstralStorm]

Did they weight it against coronary disease endpoints, of which we have numerous studies, some even with pure nicotine?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958544/

All case mortality is worse in nicotine users.