[dekhn]

Personally, I prefer the classic textbook approach, so I recommend Principles of Biochemistry (Lehninger), Biological Sequence Analysis (Durbin, Eddy, Krogh, Mitchison) which is sadly pretty dated now, a general Biology (Campbell), and finally if you really want to dive down the rabbit hole of a complex biological problem with huge health applications, Biology of Cancer (Weinberg).

I've had this argument with folks before and some people seem fine learning in other ways, but I really prefer the textbook approach, especially textbooks which are basically just summaries of the current understanding of the field, with direct links to the detailed review articles.