[Fomite]

I mean, if it is genuinely a whole population cohort, there's a legitimate question to what "power" even means in that context, because there's no statistical uncertainty. It simply is.

Whether or not hypothesis testing in registry data is justifiable was once the topic of a legendary fight in my graduate department during someone's defense.

[throwawayhhakdl]

No that’s not correct.

I mean if we’re evaluating the claim that no blind people got schizophrenia then sure. But the claim is that blind people don’t get schizophrenia, which is different. The population for this claim is not “all the humans alive” but rather “all potential humans” (which is not possible to sample).