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Having witnessed at least 100 sessions, there are no long-term changes beyond the participant having intimately experienced some aspect of the infinite (whether it be harrowing or blissful) and as a result knowing that that potentiality exists. Behaviorally most just go back to the same patterns and aren't particularly changed. Ayahuasca, due to the before/after dietary constraints, is more effective (IMO) in inducing lifestyle changes. That said, 5MeO is the death experience (i.e. it very likely mirrors the experience at the moment of physical death) and is, if nothing else, great practice for the real thing :) In terms of adverse effects, some wounded warriors take days, weeks, or even months to heal, but that's the same for any psychedelic, a segment of the population will be adversely affected. Also, 5MeO can be abused; I've encountered at least one facilitator who takes it daily (over 3K journeys), which seems somewhat excessive, and can be seen in their flat affect (i.e. you'd expect such a being to radiate joy if number of journeys === depth of experience). |
From what i read of the Johns Hopkins studies using psychedelics to quit smoking, CBT style sessions before the psychedelics was a key part of the program.