Running any resilient storage system without ECC RAM is warned against, people just really make a big deal about it with ZFS. If your data in RAM is corrupted before it makes it to the hard drive, pretty much any file system is going to write corrupted data to the drive.
It becomes even worse when RAM Is usually only tested when the computer is built.
I've had several cases where RAM becomes faulty a couple of years down the road.
Recently I had a very weird case of two stick of four went bad due to only moving the computer from one corner to the next without even opening the case.