[johnc1231]

It might vary from field to field, but in genetics Excel is a complete nonstarter, and even numpy is not going to work on sufficiently large datasets. The project I work on, http://hail.is, was started to help deal with this.

[dang]

It doesn't look like that project has been discussed on HN before. One of you should definitely post it! If you email [e-mail] we can give you some tips on how to do that, and possibly also put the submission in the second-chance pool (described at https://news.ycombinator.com/item?id=11662380).