[himinlomax]

Well the position being discussed, different from the current consensus, is that what sets apart the "cancer" condition from routine mutated cell line is metabolism, not immunity to the immune (!) system.

In that spirit, subsequent mutations that confer resistance can be seen as a consequence of this abnormally high metabolism rate that overwhelm the system and also cause increasing mutation rates.

In conclusion, while cancer may indeed become a complicated condition to treat, the root cause thus defined is rather simple. Whether this paradigm is valid and useful is an open question, but the article being discussed sure seems to point that way.