[gewa]

It's true, that different codons are transcribed with different speed but I've never heard that this would lead to differences in folding. Speed of translation is nevertheless used in order to signal shortage of amino acids or to implement modification.

When you're doing protein expression, it's a standard procedure to do a codon optimization in order to adapt the codons to your host expression system. When you're expressing a human protein in yeast or ecoli the codons will be quite different but the folding is the same. If translation wouldn't show this stability it would be difficult to use foreign expression systems at all.