Hacker News new | ask | show | jobs
by waserwill 2348 days ago
Maybe you know this, but: Interpreting DNA methylation isn't straightforward. Since it's involved in gene regulation and cell differentiation, it's variable across cells. Due to regulatory networks, whether any particular methylated region is responsible for some outcome may also be unclear.

That being said, if you have reason to believe that the knowledge will help, or are just curious, feel free

1 comments

sure, I understand that, but from what I saw the data isn’t that hard to process either, there are multiple R libraries actually that help, I’m currently also learning Genomics Analysis Harvard course at edx.org.

I already found multiple papers published in the last few years that identified the important locations with methylation changes, and those targets map to known illneses.

I tried to go to many doctors, but as they couldn’t measure any important changes with their toolboxes, they all sent me to psychologists.

Thanks for offering help, I’m always interested in learning more about genomics, though right now my plan is to learn by reproducing some articles that I read that contain methylation data sets (after the Harvard course).