[JohnJamesRambo]

I can see people keeping some Zantac in their car and that gets quite hot (140+) in the summer.

I don’t think the penalty for not storing your medicine quite right should be ingesting a carcinogen.

[Tagbert]

It was 130C / 260F that is considerably higher than the inside of a car.

Still, this suggests that ranitidine may not be stable and its breakdown products may be risky. If mixing it with nitrite produces NDMA under condition found in the stomach that is another risk case. I wonder if there is any breakdown over time just sitting on the shelf?

[JohnJamesRambo]

Oh I didn’t notice that. Then I agree this is silly. No you should not heat your Zantac to 266 F haha.

[JshWright]

I assume that's 140 Fahrenheit. The testing in question was conducted at 140 Celsius (which is quite a bit warmer...).

I also think it's unlikely that those people who are keeping their meds in their car are also keeping their meds dissolved in a solution with high levels of nitrite.

[sansnomme]

If the temperature in your car is 140 Celsius, you have bigger problems than carcinogenic medicine.

[waste_monk]

Or rather, you should stop driving your oven.

[deschutes]

The article is highly misleading. in the heating test, they heated the drug to 130 C, far beyond the temperature you'll find in a car. The gastric simulation with nitrites seems legit though.

[syshum]

Failing to follow manufacturers directions should not result in a Recall, it is not their fault people are stupid