Yeah, I can recommend it too. I experienced wrist numbness and pain, and they went away completely after I started using it. Originally I just wanted a vertical mouse, but MX Ergo is both vertical and a trackball. Go with MX Ergo Plus if you can, it has an additional wedge increasing the angle even more.
The only thing I have a problem with on this is the rubber coating on the metal plate. It's not sticking any more to the one I have at home. It seems like it's not a problem with the Plus but since I didn't know it even existed before your comment and I bought 2 of the normal ones (in case they go out of production...I have large hands and there are not many good products out there), it's not a solution for me.