[hannasanarion]

Not this one. The answer is yes, we will run out of helium, it is one of the few truly non-renewable resources. You can use chemical processes to make methane or petroleum-equivalents, and coal can be replaced with charcoal, but once all the helium atoms have drifted off into space, they're gone forever.

It just won't happen soon.

[amanaplanacanal]

We’ll be able to fuse our own before that happens. Or go fetch it from elsewhere.

[Accujack]

FYI, our sun is also going to go out.

Just so you can plan ahead.