It's doubly funny, because we actually have not enough of an idea how muscles do what they do... Even so far as immune system may be involved in their growth and strength adaptation.
I don't think so, no. Here is why: the basic behavior of muscles are decently well understood. For example why and how they contract and relax, and why they tire. We know of several reasons why muscles might malfunction. What is not well established is how and why muscles become stronger over time.
Compare this to for example ego depletion, and I would say that the analogy is not apt.