| There only have been a couple antibiotic studies, it's hard to get funding for more elaborate studies because of the controversy. Those studies ignore the research on biofilms and only gave antibiotics for a couple weeks. And even in those flawed studies there was a marked improvement in quality of life for Lyme patients. Let's take the PLEASE[0] study for example.
Although significant improvement in health was measured (on average 4.6 points on the SF-36 scale; 3 points is considered significant progress) the results were presented with the headline: 'Long-term use of antibiotics does not benefit long-term complaints of Lyme'. While tens of thousands of patients have been cured by a cocktail of antibiotics taken for several months or sometimes years. This is also what the current in vitro research is showing. Lyme persisters can only be killed by a combination of antibiotics.[1] Like tuberculosis. And it's also what this data analysis of 200 patients shows.[2] >We collected data from an online survey of 200 of our patients, which evaluated the efficacy of dapsone (diaminodiphenyl sulfone, ie, DDS) combined with other antibiotics and agents that disrupt biofilms for the treatment of chronic Lyme disease/post-treatment Lyme disease syndrome (PTLDS).
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Conclusion
DDS CT decreased eight major Lyme symptoms severity and improved treatment outcomes among patients with chronic Lyme disease/PTLDS and associated coinfections. And recently we have the spectacular results of Disulfiram.[3] A clinical trial is underway at Colombia University so we won't have offical results until 2021 but all signs point to it being a gamechanger. Lyme communities are full of people with miracle stories after taking Disulfiram. [0]https://www.nejm.org/doi/full/10.1056/NEJMoa1505425 [1]https://www.jhsph.edu/news/news-releases/2019/three-antibiot... [2]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388746/ [3] https://www.ncbi.nlm.nih.gov/pubmed/31151194 |