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by mabcat 2405 days ago
We ran a clinical trial of a very common antidepressant. Blinding was difficult because on the active arm damn near everyone had observable side-effects within 40 minutes of administration. Clearly not related to the placebo effect in this case, only the pharmacist knew what was in the capsules until the nausea started.
1 comments

>Clearly not related to the placebo effect in this case, only the pharmacist knew what was in the capsules until the nausea started.

Right, and it could only be the placebo effect if those capsules contained sugar.